Accelerating the implementation of genomics technologies for actionable insights
We are a dedicated team of experts determined to enhance public health outcomes through the innovative implementation of NGS and bioinformatics technologies. Together, we draw upon experience from academic, governmental, and industry careers to deliver a world-leading service across a diverse range of microbial genomics applications, including infectious disease, food safety, molecular diagnostics, and environmental monitoring.
Pathogen genomics is crucial to many modern public health, diagnostics, environmental monitoring and food safety approaches. It enables the identification and tracking of disease-causing microbes while aiding in the development of effective treatments, policies and disease prevention strategies.
Next-generation sequencing (NGS) plays a pivotal role in pathogen genomics. It offers a means to read the genetic code of disease-causing microbes and it provides critical insights into microbial diversity, evolution and key virulence factors.
Here at Theiagen Genomics, we utilize the latest NGS approaches, develop helpful resources and train personnel to the highest level. We seamlessly integrate technology and build capacity in your workflows as your expert partner in pathogen genomics.
Pathogen genomics requires highly technical expertise to be done well. That’s why we offer personalized training in the latest sequencing and bioinformatics technologies tailored to your needs.
Whether it’s on-site or remote, one hour or one week, our training experts can equip your team with the skills they need to excel.
Our comprehensive support goes beyond technical assistance – it includes a deep understanding of your data, providing flexible terms and generating key insights for workflow innovation.
Whether your project is large or small, we offer the same support regardless of your scale or throughput needs.
Team up with Theiagen today and leverage our expertise for your success.
Upload your data directly or import it from your sequencing instrument for a seamless transfer, or retrieve it from a public or private repository.
We piece together genetic information from your data to form a genome assembly. Then, we conduct Quality Control (QC), functional characterization, drug resistance and virulence prediction and pathogen specific characterization steps.
We generate comprehensive reports to serve as your project guide. We present your results and findings in an easy-to-read format that supports further research and proactive decision-making.
We map the evolutionary history and relationships between different organisms within your sample. We guide you to evaluate pathogen risk and pinpoint optimal solutions.
Share your data with the wider scientific community by depositing it into a public repository to ensure that your findings contribute to the broader body of knowledge. Our experts can help with the complex challenge to best practices.
Read about how our work has enabled peer-reviewed scientific papers.
In this study, direct metagenomic sequencing approaches were used to assess the possibility of replacing genome sequences with metagenome sequences; metagenomic sequencing outputs were used to describe clinically relevant attributes of Campylobacter genotypes.
In this study, direct metagenomic sequencing approaches were used to assess the possibility of replacing genome sequences with metagenome sequences; metagenomic sequencing outputs were used to describe clinically relevant attributes of Campylobacter genotypes.
Abstract The detection, characterization, and monitoring of SARS-CoV-2 recombinant variants constitute a challenge for public health authorities worldwide. Recombinant variants, composed of two or more SARS-CoV-2 lineages, often have unknown impacts on transmission, immune escape, and virulence in the early stages of emergence. We examined 4213 SARS-CoV-2 recombinant SARS-CoV-2 genomes collected between 2020 and 2022 in California to describe regional and statewide trends in prevalence.
Abstract The detection, characterization, and monitoring of SARS-CoV-2 recombinant variants constitute a challenge for public health authorities worldwide. Recombinant variants, composed of two or more SARS-CoV-2 lineages, often have unknown impacts on transmission, immune escape, and virulence in the early stages of emergence. We examined 4213 SARS-CoV-2 recombinant SARS-CoV-2 genomes collected between 2020 and 2022 in California to describe regional and statewide trends in prevalence.
Five years before the 2022–2023 global mpox outbreak Nigeria reported its first cases in nearly 40 years, with the ongoing epidemic since driven by sustained human-to-human transmission. However, limited genomic data has left questions about the timing and origin of the mpox virus’ (MPXV) emergence. Here we generated 112 MPXV genomes from Nigeria from 2021-2023.
Five years before the 2022–2023 global mpox outbreak Nigeria reported its first cases in nearly 40 years, with the ongoing epidemic since driven by sustained human-to-human transmission. However, limited genomic data has left questions about the timing and origin of the mpox virus’ (MPXV) emergence. Here we generated 112 MPXV genomes from Nigeria from 2021-2023.
Fast, efficient public health actions require well-organized and coordinated systems that can supply timely and accurate knowledge. Public databases of pathogen genomic data, such as the International Nucleotide Sequence Database Collaboration (INSDC), have become essential tools for efficient public health decisions. However, these international resources began primarily for academic purposes, rather than for surveillance or interventions.
Fast, efficient public health actions require well-organized and coordinated systems that can supply timely and accurate knowledge. Public databases of pathogen genomic data, such as the International Nucleotide Sequence Database Collaboration (INSDC), have become essential tools for efficient public health decisions. However, these international resources began primarily for academic purposes, rather than for surveillance or interventions.
Fast, efficient public health actions require well-organized and coordinated systems that can supply timely and accurate knowledge. International standards help share genomic data about pathogens which are of a public health concern. Theiagen contributes directly to these standards with everyone benefiting.
Fast, efficient public health actions require well-organized and coordinated systems that can supply timely and accurate knowledge. International standards help share genomic data about pathogens which are of a public health concern. Theiagen contributes directly to these standards with everyone benefiting.
California COVIDNet, a collaborative initiative for SARS-CoV-2 genomic surveillance, involved 50 partners and overcame data and computational challenges. Since March 2021, it has sequenced over 450,000 genomes, contributing to nearly 800,000 in total, covering all California regions and representing over 5% of the state's positive tests.
California COVIDNet, a collaborative initiative for SARS-CoV-2 genomic surveillance, involved 50 partners and overcame data and computational challenges. Since March 2021, it has sequenced over 450,000 genomes, contributing to nearly 800,000 in total, covering all California regions and representing over 5% of the state's positive tests.
Public health labs rapidly adopted whole-genome sequencing for SARS-CoV-2, leading to the development of COVIDNet by the California Department of Public Health. This scalable, cloud-based initiative serves as a model for worldwide public health labs, offering insights into bioinformatics, genomic surveillance, best practices for data sharing, and enhancing collaboration between laboratory scientists and epidemiologists.
Public health labs rapidly adopted whole-genome sequencing for SARS-CoV-2, leading to the development of COVIDNet by the California Department of Public Health. This scalable, cloud-based initiative serves as a model for worldwide public health labs, offering insights into bioinformatics, genomic surveillance, best practices for data sharing, and enhancing collaboration between laboratory scientists and epidemiologists.
We have adopted an open bioinformatics ecosystem to address the challenges of bioinformatics implementation in public health laboratories (PHLs). Bioinformatics implementation for public health requires practitioners to undertake standardized bioinformatic analyses and generate reproducible, validated and auditable results.
We have adopted an open bioinformatics ecosystem to address the challenges of bioinformatics implementation in public health laboratories (PHLs). Bioinformatics implementation for public health requires practitioners to undertake standardized bioinformatic analyses and generate reproducible, validated and auditable results.
Explore our research and contributions in the field.
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