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Pathogen genomics, made operational

Pathogens. Understood.™

From complexity to clarity.

Achieving true clarity on pathogens requires genomic science — along with the systems and strategy to act on it. Theiagen brings expertise across all three.

Two laboratory specialists review pathogen genomic analysis beside sequencing instruments
Why It Matters

Every pathogen challenge demands a clear answer.

Genomics can deliver high-resolution insights. Realizing that potential takes the right expertise, systems, and strategy.

The threat landscape

Pathogens are evolving and spreading - more variants, more antimicrobial resistance, and more emergence across borders and populations.

The capability gap

Generating sequencing data is no longer the bottleneck. Building the right approach and program to turn that data into useful insights is.

The expertise gap

Microbiology, bioinformatics, epidemiology, and computer science are each specialized disciplines. Assembling and operationalizing all four around a specific environment is rarely straightforward.

What Makes Theiagen Unique

Science, systems, and strategy

Our breadth of expertise comes from working across pathogen challenges with labs of every kind. We structure each engagement around our clients’ needs.

Science

The full range of disciplines working together. Theiagen’s scientific depth spans microbiology, bioinformatics, epidemiology, and software systems - the complete range required to understand and operationalize pathogens at a genomic level.

Learn more about Science

Systems

Built around what you already have. We build the workflows, pipelines, and technology infrastructure that turn genomic data into clear, defensible answers within your existing environment.

Learn more about Systems

Strategy

Every engagement is different. We listen first, then structure an approach around exactly what you need - nothing more, nothing less.

Learn more about Strategy
Why Theiagen

Why organizations choose Theiagen

Theiagen is strongest at the handoff between complex genomic evidence and the people who have to act on it.

90+laboratories supported
40countries represented
4disciplines aligned
01

Judgment under pressure

Specialists who understand what genomic evidence can and cannot support when timelines, reporting duties, and public-health stakes are real.

02

Methods teams can defend

Transparent workflows, documentation, and quality patterns that help teams explain results instead of treating analysis as a black box.

03

Programs that survive change

Design choices account for staff turnover, new pathogens, shifting platforms, and the practical maintenance burden after launch.

04

Collaboration without hand-waving

Scientific, technical, and operational conversations stay connected so recommendations do not collapse at implementation.

05

Capability transfer

Training and handoff are built into the work so clients gain more confidence and independence over time.

Collaborative by design

Partnerships that strengthen the work.

We collaborate across laboratories, technology platforms, and public-health networks to move genomic programs forward.

SeqCoast GenomicsTerraClear LabsAPHLSeqera Labs
Insights from the Field

What we’re seeing on the front lines of pathogen genomics

Theiagen shares what we’re learning from the lab, from the field, and from genomic outbreak intelligence work.

Case studies

Examples include unclear infection investigations, Candida auris outbreak insight, and California COVIDNet surveillance scale.

Learn more about Case studies

Resources

Public resources, publications, training, podcast episodes, technical briefs, and newsletters.

Visit resources
Answers at a glance

Frequently Asked Questions

Clear answers to common questions about how Theiagen works, what we build, and who we support.

What is pathogen genomics?

Pathogen genomics is the use of DNA and RNA sequencing to understand infectious organisms, including bacteria, viruses, fungi, and parasites. By analyzing genomic data, laboratories can identify outbreaks, track transmission, detect emerging variants, and support public health decision-making.

Why is pathogen genomics important?

Pathogen genomics provides a level of detail that traditional laboratory methods cannot match. It helps organizations determine how pathogens are related, monitor antimicrobial resistance, identify transmission pathways, and improve outbreak response and public health bioinformatics programs.

How does genomic sequencing improve infectious disease detection?

Genomic sequencing reveals genetic relationships among pathogens that are not visible through conventional testing. This allows laboratories and public health agencies to identify outbreaks earlier, understand transmission dynamics, and make more informed decisions using standardized public health genomic pipelines.

What types of organizations use pathogen genomics?

Pathogen genomics is used by public health laboratories, federal agencies, commercial reference laboratories, hospital and health systems, food and water safety organizations, and academic and research institutions.

What does Theiagen do?

Theiagen combines microbiology, bioinformatics, epidemiology, and software systems to help organizations build sustainable pathogen genomics capabilities rather than isolated tools.

What makes Theiagen different from other genomics companies?

Theiagen specializes in pathogen genomics and pairs scientific depth with operational implementation, transparent workflows, training, and ongoing expert support.

Why do organizations need more than sequencing equipment?

Sequencing equipment alone does not create a successful pathogen genomics program. Effective programs require NGS pipeline automation, bioinformatics workflows, data interpretation, quality systems, and trained personnel who can translate genomic information into decisions and actions.

What does "From complexity to clarity" mean?

The phrase reflects Theiagen’s approach of helping organizations transform complex genomic data into clear, defensible, and actionable answers for surveillance, outbreak response, and public health decision-making.

What is NGS pipeline automation and why does it matter?

NGS pipeline automation uses standardized, reproducible workflows to process raw sequencing data with minimal manual intervention. Automated pipelines reduce errors, improve throughput, and make genomic programs more scalable and sustainable.

What is cloud-based genomic analysis?

Cloud-based genomic analysis uses scalable cloud computing infrastructure to process, store, and interpret genomic sequencing data. It supports collaboration, large-scale surveillance, and rapid scaling during outbreak response.

How does Theiagen approach genomic data security and compliance?

Genomic data security and compliance are built into engagements from the outset, including alignment with applicable regulatory frameworks, data governance, IP protection, and secure cloud or on-premises infrastructure configuration.

Does Theiagen use open-source bioinformatics tools?

Yes. Theiagen’s workflows are built on open-source bioinformatics tools including Nextflow, WDL, and publicly available pipeline frameworks wherever appropriate, supporting transparency, reproducibility, interoperability, and practical reuse across public health and laboratory environments.

How does Theiagen compare to other bioinformatics consulting companies?

Unlike generalist bioinformatics consulting firms, Theiagen specializes in pathogen genomics and combines microbiology, bioinformatics, epidemiology, and software systems under one engagement.

Ready to find clarity for your pathogen challenge?

Let’s start with a conversation.