Develop Your Bioinformatics Workflow with Theiagen
Next-generation sequencing (NGS) plays a pivotal role in pathogen genomics, offering a means to read microbes’ genetic material for insights into their diversity, evolution, drug resistance, and critical virulence factors.
We Build Capacity
Here at Theiagen, we utilize the latest bioinformatic approaches, develop resources, and train your personnel to seamlessly integrate cutting-edge technology and build capacity in your public health workflows.
Integrating WDL with Workflow Management Systems
Detailed and reproducible workflows outline the specific tasks, inputs, outputs, and dependencies required for sequencing data analysis. These workflows can be created through Workflow Description Language (WDL) and executed in workflow management systems such as the Terra cloud-based bioinformatics platform from the Broad Institute.
WDL can execute tasks such as data preprocessing, alignment, variant calling, quality control, and downstream analysis. It can be integrated into existing workflows and is compatible with tools and software commonly used in NGS data analysis, including Terra and Manifold.
WDL is associated with the Broad Institute and is used across bioinformatics projects. It provides a rigorous and expressive structure and is well integrated with Terra’s cloud-based workflow execution and data-management environment. Workflows are validated before execution, helping support correct and reproducible pathogen-genome analysis.